Controlled Human Infection Challenge Studies: Lessons from Malaria towards COVID-19
Controlled Human Infection Challenge Studies involve the deliberate infection of healthy volunteers to support clinical vaccine development, for example for malaria. This webinar will discuss ethical and scientific principles for such studies, outline the risk mitigation steps taken in previous malaria human challenge studies, explore how this might be applied in the context of COVID-19 vaccine development, and address ethical and practical concerns.
Webinar Faculty:
- Marco Cavaleri, Head of Office, Anti-infectives and Vaccines, European Medicines Agency (EMA), Amsterdam, The Netherlands
- Euzebiusz Jamrozik, Monash Bioethics Centre, Monash University, Melbourne, Australia
- Melissa Kapulu, Kenya Medical Research Institute, Nairobi, Kenya
- Katherine Littler, Global Health Ethics Team, World Health Organization, Geneva, Switzerland
- Colin Pillai, CP+ Associates and Pharmacometrics Africa, Basel (Switzerland) and Cape Town (South Africa)
- Andrew J Pollard, Professor of Paediatric Infection and Immunity, University of Oxford, Oxford, England
- Bernd Rosenkranz, Fundisa African Academy of Medicines Development NPC, Schwielowsee (Germany) and Cape Town (South Africa)
- Getnet Yimer, Regional Director for Global One Health Initiative of the Ohio States University in East Africa, Addis Ababa, Ethiopia
Moderated by:
- Claudia I. Emerson, Director, Institute on Ethics & Policy for Innovation, McMaster University, Hamilton, Canada