Professor Saye Khoo
University of Liverpool
UK
Professor Saye Khoo, MD, PhD, is Honorary Consultant Physician in Infectious Diseases at the Royal Liverpool University Hospital, and Professor in the School of Biomedical Sciences at the University of Liverpool.
His research focuses on the pharmacology of HIV treatment failure and how therapy may be improved through individualised care through understanding of why drug exposure varies markedly between individuals (and the role of individual characteristics such as weight, gender, host genetics and drug interactions), and identify vulnerable groups who are at particular risk of failure, or toxicity. These studies span bench science, through translational research and into the clinic, and onwards to population based modelling approaches.
He leads the AGILE Coronavirus Drug Testing Initiative, which seeks to investigate new molecules as potential treatment for COVID-19. His lab also works to measure drug concentrations of these new therapies, in order to optimise the dosing. They have a large drug interactions programme to prevent harm arising from multiple treatments in people with many underlying medical conditions, which may interact with experimental COVID-19 therapies.